中药离子导入联合常规治疗肝郁脾虚慢性乙型病毒性肝炎随机平行对照研究

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[目的]观察中药离子导入联合常规治疗肝郁脾虚慢性乙型病毒性肝炎疗效。[方法]使用随机平行对照方法,将60例住院和门诊患者按就诊顺序编号简单随机分为两组。对照组30例抗病毒、护肝降酶、中药对症等常规治疗。治疗组30例肝病治疗仪中药离子导入。选穴:阳陵泉、足三里、阴陵泉、阿是穴、肝俞、期门、章门;离子导入:柴胡、白术各150g,水煎350m L,放入烧杯中,通过电热恒温水箱加热至100℃浓缩成300m L,10m L/次,用2×2cm纱布浸取药汁贴于肝病治疗仪电极板上,嘱患者平卧位或坐位,照上述穴位放置,Ⅰ、Ⅱ、Ⅲ三个频率交替使用,以Ⅰ频为主,30min/次,1次/d,6次/周;常规治疗同对照组。连续治疗4周为1疗程。观测临床症状、肝功能指标(ALT、AST、TBIL)、症状积分、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈7例,有效21例,无效2例,总有效率93.33%。对照组痊愈4例,有效20例,无效5例,总有效率80.00%。治疗组疗效优于对照组(P<0.05)。临床症状积分、肝功能指标(ALT、AST、TBIL)两组均有改善(P<0.01),治疗组改善优于对照组(P<0.05)。[结论]中药离子导入联合常规治疗肝郁脾虚型慢性乙型病毒性肝炎,疗效满意,无严重不良反应,值得推广。 [Objective] To observe the effect of traditional Chinese medicine iontophoresis combined with routine treatment of chronic hepatitis B with liver depression and spleen deficiency. [Methods] Using randomized parallel control method, 60 cases of inpatients and outpatients were randomly divided into two groups according to the sequence number of visiting doctor. Control group of 30 cases of anti-virus, liver descending enzyme, traditional Chinese medicine symptomatic treatment. Treatment group of 30 cases of liver disease treatment instrument Chinese iontophoresis. Choice of points: Yanglingquan, Zusanli, Yinlingquan, Ashi points, liver Yu, the door, chapter door; Ion: Bupleurum, Atractylodes each 150g, decoction 350m L, into the beaker, heated by electric thermostat Water tank was heated to 100 ℃ concentrated to 300m L, 10mL / times, with 2 × 2cm gauze leaching juice attached to the liver treatment instrument electrode plate, Zhu Huanzhe supine or sitting, according to the above-mentioned acupuncture points, Ⅰ, Ⅱ, Ⅲ alternating use of three frequencies to I-based, 30min / times, 1 time / d, 6 times / week; conventional treatment with the control group. Continuous treatment for 4 weeks for a course of treatment. Observed clinical symptoms, liver function indicators (ALT, AST, TBIL), symptom scores, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] In the treatment group, 7 cases were cured, 21 cases were effective and 2 cases were ineffective. The total effective rate was 93.33%. In the control group, 4 cases were cured, 20 cases were effective, 5 cases were ineffective, and the total effective rate was 80.00%. The treatment group was better than the control group (P <0.05). Clinical symptom score, liver function indexes (ALT, AST, TBIL) were improved in both groups (P <0.01), treatment group improved better than the control group (P <0.05). [Conclusion] The traditional Chinese medicine iontophoresis combined with conventional treatment of chronic hepatitis B with liver depression and spleen deficiency syndrome has satisfactory curative effect and no serious adverse reactions, which deserves promotion.
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