虽然人疱疹病毒8型(HHV-8)被认为是卡波济氏肉瘤的致病因子.但其在人群中的血清流行病学、传播方式与自然病程了解甚少。为此,作者在美国旧金山市进行一项男子健康研究,对HHV-8在人群中的血清流行病学特征以及HHV-8与卡波济氏肉瘤的相关性进行了调查。 这项研究始于1984年6月,在一个人免疫缺陷病毒(HIV)感染高发区的男性居民中进行,选取已感染与未感染HIV的25～54岁男 Although human herpesvirus type 8 (HHV-8) is thought to be a causative agent of Kaposi’s sarcoma, its serological epidemiology, mode of transmission, and natural history in humans are poorly understood. To this end, the authors conducted a men’s health study in the city of San Francisco in the United States to investigate the serological epidemiology of HHV-8 in humans and the association between HHV-8 and Kaposi’s sarcoma. The study began in June 1984 with men living in high-risk areas of human immunodeficiency virus (HIV) infection, selecting 25- to 54-year-old men who had or had not been infected with HIV