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山楂提取物(CE)在德国被用于治疗轻、中度心衰(NYHAⅡ),但对其在心脏电生理方面的功效知之甚少。最近有文献报道,CE能够延长离体灌流心脏的不应期,并延长豚鼠乳突肌动作电位时间。本研究旨在探讨CE延长动作电位时间的作用机制。利用电压钳技术就CE对单个离
Hawthorn extract (CE) is used in Germany to treat mild to moderate heart failure (NYHAII), but little is known about its effect on cardiac electrophysiology. It has been reported recently that CE can prolong the refractory period of isolated perfused hearts and prolong the action potential duration of guinea pig mastoid. The purpose of this study was to investigate the mechanism by which CE extends action potential duration. Using voltage clamp technology for CE to single