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目的 :探讨酚妥拉明、多巴胺联合应用治疗新生儿硬肿症的疗效。方法 :将 72例新生儿硬肿症患儿随机分为两组 :治疗组 (n =38)除常规治疗外静脉滴注酚妥拉明、多巴胺 ;对照组 (n =34)给予复温、吸氧、补液、纠酸、支持治疗、抗感染等常规治疗。结果 :治疗组用药 2 4h硬肿面积开始缩小 ,完全消失时间为 3 9± 1 1天。对照组用药 48h硬肿面积开始缩小 ,完全消失时间为 5 5± 1 2天 (t=2 .36 ,P <0 0 5 )。结论 :酚妥拉明、多巴胺联合应用可使硬肿开始消退时间及完全消失时间明显提前 ,缩短病程 ,且无明显副作用 ,值得推广应用
Objective: To investigate the curative effect of phentolamine and dopamine in the treatment of neonatal sclerema. Methods: Seventy-two infants with scleredema were randomly divided into two groups: the treatment group (n = 38) received intravenous infusion of phentolamine and dopamine, while the control group (n = 34) Oxygen, rehydration, acid correction, supportive treatment, anti-infection and other conventional treatment. Results: In the treatment group, the area of edema began to decrease after 24 hours of treatment, and the complete disappearance time was 39 ± 11 days. Control group 48h edema area began to shrink, the complete disappearance of time was 5 ± 12 days (t = 2.36, P <0 05). Conclusion: The combination of phentolamine and dopamine can significantly reduce the onset time and complete disappearance of sclerosis, shorten the course of the disease and have no obvious side effects, which is worthy of promotion and application