作者在以往的实验中发现,吡喹酮对曼氏血吸虫的作用是建立在宿主具有健全的免疫应答功能的基础上,并发现经吡喹酮治疗后的小鼠,从其体内获得的虫体上有能与虫体表皮相结合的抗体。吡喹酮的作用机制被认为是对虫体表皮的破坏。过去的实验结果提示,化疗促使虫体表面某些分子位点暴露, The authors found in previous experiments that the effect of praziquantel on Schistosoma mansoni was based on the host’s robust immune response and found that mice treated with praziquantel and parasites obtained from their body There are antibodies that bind to the epidermis of the worm. The mechanism of action of praziquantel is thought to be damaging to the epidermis of parasites. Past experimental results suggest that chemotherapy to promote the surface of some insect body site exposure,