微泡是一种内含气体的微球,由于其声学阻抗较软组织及血液低,可以作为一种声学造影剂注入体内,增加各组织之间的声学差异,进而提高超声辅助诊断疾病的能力。新近发现,微泡不仅具有诊断疾病的作用,还具有携带药物或基因达到靶向治疗疾病的能力。目前基因治疗的常用载体有病毒和非病毒两种,但在转染率和安全性方面两者均不可兼顾。微泡 Microbubbles are gas-containing microspheres that, due to their lower acoustic impedance than soft tissue and blood, can be injected into the body as an acoustic contrast medium to increase the acoustic differences between the tissues and thus enhance the ability of ultrasound-assisted diagnosis of the disease. It has recently been found that microbubbles not only have the function of diagnosing diseases, but also have the ability to carry drugs or genes to target the treatment of diseases. At present, common vectors for gene therapy are both viruses and non-viruses, but neither can be considered in terms of transfection efficiency and safety. Microbubbles