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目的 探讨肝癌肾上腺转移的放射治疗效果。方法 回顾性总结本院 2 2例肝癌肾上腺转移病人 ,用 6MX或 15MV光子 ,进行肾上腺病灶外照射 ,剂量 36～ 5 4Gy ,中位剂量 5 0Gy。结果 14例肾上腺转移病人出现疼痛症状 ,外放疗后 11例 (78 6 % )疼痛得到完全缓解 ;2例(14 3% )得到明显缓解 ,但仍需要止痛药治疗 ;73% (15 /2 2 )病例的肿瘤明显缩小 ;全部病例中位生存期为 10个月 ;未出现因肾上腺转移灶致死病例 ;副作用轻微。结论 肝细胞肝癌肾上腺转移对放射治疗敏感 ,5 0Gy的放疗剂量是比较安全的姑息性治疗。
Objective To investigate the radiotherapy effect of adrenal metastasis of liver cancer. Methods We retrospectively reviewed 22 cases of adrenal metastases from patients with hepatocellular carcinoma who were treated with 6MX or 15MV photons for external adrenal irradiation at a dose of 36-5 4GY with a median dose of 50 Gy. Results Pain was found in 14 patients with adrenal metastasis. Pain relief was completely relieved in 11 patients (78.6%) after radiotherapy. Pain relief was relieved in 2 patients (14.3%), but analgesics were still required. 73% (15/2 2) ) Cases of the tumor was significantly reduced; all cases of median survival was 10 months; did not appear due to adrenal metastasis fatal cases; minor side effects. Conclusion Hepatocellular carcinoma adrenal metastasis is sensitive to radiotherapy, and radiotherapy dose of 50 Gy is safer palliative treatment.