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目的:探讨辛伐他汀联合拜阿司匹林治疗急性脑梗死的临床疗效。方法:将160例患者随机分为治疗组和对照组,每组80例,治疗组每晚给予拜阿司匹林(100 mg)及辛伐他汀片(40mg)治疗,对照组每晚给予拜阿司匹林(100 mg)治疗。治疗90d后评价疗效。结果:治疗组总有效率76.0%,对照组总有效率62.0%(P<0.05);神经功能缺损程度评分治疗后较治疗前两组均有所改善,差异有统计学意义(P<0.05),治疗组较对照组治疗后相比,差异有统计学意义(P<0.05)。结论:辛伐他汀片治疗急性脑梗死可明显降低患者NHISS评分,临床效果显著。
Objective: To investigate the clinical efficacy of simvastatin combined with aspirin in the treatment of acute cerebral infarction. Methods: 160 patients were randomly divided into treatment group and control group, 80 cases in each group. The treatment group was treated with aspirin (100 mg) and simvastatin tablets (40 mg) nightly. The control group was given aspirin 100 mg) treatment. 90d after treatment evaluation of efficacy. Results: The total effective rate was 76.0% in the treatment group and 62.0% in the control group (P <0.05). The score of neurological deficit after treatment was significantly improved compared with the two groups before treatment (P <0.05) , The treatment group compared with the control group after treatment, the difference was statistically significant (P <0.05). Conclusion: Simvastatin tablets can significantly reduce the NHISS score in patients with acute cerebral infarction. The clinical effect is significant.