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目的探讨急性心肌梗死(AMI)并发室性心动过速(VT)和(或)心室颤动(VF)静脉注射胺碘酮的临床疗效。方法82例急性心肌梗死病人,左室射血分数0.497±0.097。室性心动过速(VT)和(或)心室颤动(VF)发作时予胺碘酮静脉负荷量后并静脉与口服维持,16例联合口服β受体阻滞剂,严密监测血压、心律和心功能,从小剂量开始逐渐加量调整至最大可耐受不影响血压又不加重心力衰竭的合适剂量。结果静脉注射胺碘酮可迅速控制AMI并发VT和(或)VF且无心力衰竭加重和血压下降,未见严重的毒副作用。结论静脉注射胺碘酮能有效地控制对常规药物无效的VT和(或)VF,降低AMI并发VT和(或)VF的死亡率。
Objective To investigate the clinical efficacy of intravenous amiodarone in patients with acute myocardial infarction (AMI) complicated by ventricular tachycardia (VT) and / or ventricular fibrillation (VF). Methods 82 cases of acute myocardial infarction patients, left ventricular ejection fraction 0.497 ± 0.097. Intravenous and oral administration of amiodarone after ventricular tachycardia (VT) and / or ventricular fibrillation (VF) was initiated and maintained intravenously. Sixteen patients received oral beta-blockers and blood pressure, heart rate and Heart function, starting from a small dose gradually adjusted to the maximum tolerated without affecting the blood pressure without exacerbating the appropriate dose of heart failure. Results Intravenous amiodarone could rapidly control AMI complicated by VT and / or VF without worsening of heart failure and blood pressure drop, with no serious side effects. Conclusion Intravenous amiodarone can effectively control the VT and / or VF which are not effective on conventional drugs and reduce the mortality of AMI complicated by VT and / or VF.