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对70例接受各种化疗的癌症病人,就枢丹与胃复安的止吐效果进行对比研究。结果表明:治疗组枢丹止吐有效率为85.6%Ⅲ~Ⅳ度恶心呕吐发生率分别为11.4%和8.6%;对照组胃复安止吐有效率为257%,Ⅲ~Ⅳ度恶心呕吐发生率分别为54.3%和45.7%。两者比较:枢丹止吐有效率明显高于胃复安组(P<0.01)。两种药物的不良反应主要有:便秘、腹部不适、腹泻及头晕。其中,以枢丹组较轻。
A comparative study of the antiemetic effects of Gandan and Ganfuan was conducted on 70 cancer patients receiving various chemotherapy. The results showed that the effective rate of dandan antiemetic in the treatment group was 85.6%, and the incidence of nausea and vomiting was 11.4% and 8.6% respectively. The effective rate of the antiemetic in the control group was 257%. Nausea and vomiting occurred in the degree III to IV. The rates were 54.3% and 45.7% respectively. Comparison of the two: the efficacy of pivotal antiemetic was significantly higher than that of the metoclopramide group (P<0.01). The adverse reactions of the two drugs are mainly: constipation, abdominal discomfort, diarrhea and dizziness. Among them, the lighter group of Dan.