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目的为了探讨能否用吸入辐射损伤小（辐射损伤仅为Ｘ线检查的１／２０～１／３０）的氙（１３３Ｘｅ），取代注射锝（９９ｍＴｃ）研究＋ＧＺ负荷下全身血液动态转移的客观规律。以便使该法能推广应用于人体。方法用吸入对于人体相当安全的组织扩散性核素１３３Ｘｅ标记犬血液，测得Ｇ负荷下由头至臀８个部位的１３３Ｘｅ的饱和及清除曲线。用去本底法进行处理，从１３３Ｘｅ的饱和及清除曲线中分离出Ｇ负荷致血容动态变化活性曲线，进行校正后与用注射非组织扩散性核素９９ｍＴｃ法测得的结果进行比较研究。结果用吸入１３３Ｘｅ示踪剂法得到的Ｇ负荷去本底清除曲线，经校正后，与用注射９９ｍＴｃ法测得的Ｇ负荷血容曲线很相似。结论可以用吸入１３３Ｘｅ法取代注射９９ｍＴｃ法，研究＋ＧＺ负荷下全身血液的动态转移规律
Objective To investigate the objective laws of whether or not xenon (133Xe), which is a small (less than 1/20 to 1/30 of the X-ray examination, radiation damage) radiofrequency injury, instead of injecting technetium (99mTc) . So that the law can be applied to the human body. Methods Inhalation of 133Xe labeled canine diffusible radionuclide, which is quite safe for human body, measured the saturation and clearance curve of 133Xe from head to hip in G load. By using the background subtraction method, the kinetic curves of the dynamic changes of blood volume induced by G load were isolated from the saturation and clearance curve of 133Xe, and then compared with the result of 99mTc injection of non-tissue diffusing radionuclide. Results The G-load deflux profile obtained by inhalation of the 133Xe tracer method was similar to the G-load BL curve measured by the 99mTc injection method. Conclusion Inhaled 133Xe method can be used instead of injection of 99mTc method to study the dynamic transfer of whole body blood under + GZ load