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美国旧金山消息:当地的科学家报告,一种内源性鸦片样物质的类似物强啡肽可延长实验引起卒中动物的存活期,并限制其神经缺陷的发生。加利福尼亚大学的研究人员说,他们的发现表明强啡肽及其类似物可能用于临床卒中病人的处理。此外,这些发现为过去认为内源性鸦片样肽类与脑局部缺血和卒中有关的看法补充了证据。以神经外科医师David S Baskin为首的小组通过手术堵塞右中脑动脉而使42只猫发生卒中。这些动物随机分为4个治疗小组:强啡肽(1-13),含有强啡肽分子中17种氨基酸中
SAN FRANCISCO, USA: Local scientists report that dynorphin, an analogue of the endogenous opioid, prolongs the survival of stroke animals and limits the development of neurological deficits. Researchers at the University of California said their findings show that dynorphin and its analogs may be used in the treatment of patients with clinical stroke. In addition, these findings complement the previous view that endogenous opioid peptides are associated with cerebral ischemia and stroke. A team led by neurosurgeon David S Baskin had stroke in 42 cats by surgically occluding the right middle cerebral artery. The animals were randomized into four treatment groups: dynorphin (1-13) containing 17 amino acids in the molecule of dynorphin