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用放免法测定结直肠癌患者外周血免疫抑制酸性蛋白（IAP）含量及白细胞总数、中性粒细胞／淋巴细胞比值，结果发现，其皆随结直肠癌病期进展而逐渐增高，IAP含量与中性粒细胞／淋巴细胞比值呈直线相关．提示检测外周血IAP含量可预测直肠癌患者病期．
The content of immunosuppressive acidic protein (IAP) and the total number of leukocytes and neutrophil/lymphocyte ratio in peripheral blood of patients with colorectal cancer were measured by radioimmunoassay. The results showed that they all gradually increased with the progression of colorectal cancer, IAP content and The neutrophil/lymphocyte ratio is linearly related. Tip detection of peripheral blood IAP content can predict the duration of disease in patients with rectal cancer.