胎粪吸入综合征(MAS)绝大部分见于足月儿和过期产儿,系在宫内和分娩时吸入了被胎粪污染的羊水,大多伴有窒息,临床主要以缺氧、酸中毒、呼吸窘迫为主要表现,常伴有其他多脏器的功能损伤,是足月儿和过期产儿常见的死亡原因。1 MAS的病理生理基础和发病机制足月儿和过期产儿因各种原因在宫内或分娩时急性或慢性持续缺氧情况下,体内血流重新分布,先要保证重要脏器(心、脑、肾上腺等)的血供,而肠道血管痉挛,肛门括约肌松弛,胎粪排出至羊水。缺氧时,胎儿 Most of meconium aspiration syndrome (MAS) seen in term infants and expired children, Department of intrauterine and childbirth inhalation of meconium-stained amniotic fluid, mostly accompanied by asphyxia, clinical mainly hypoxia, acidosis, respiratory Distress as the main manifestation, often accompanied by multiple organ damage, is the common cause of death in term and expired children. 1 Pathophysiology of MAS and its pathogenesis Full-term infants and children with obsolete birth due to various reasons in the uterus or childbirth acute or chronic hypoxia, the body redistribution of blood flow, we must first ensure that the vital organs (heart, brain , Adrenal, etc.) blood supply, and intestinal vasospasm, anal sphincter relaxation, meconium discharge to amniotic fluid. Hypoxia, the fetus