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目的探讨老年代谢综合征(MS)患者24h动态血压、24h脉压与其靶器官损害的关系。方法将92例单纯老年高血压患者、88例单纯老年MS患者和117例伴靶器官损害的老年MS患者24h动态血压监测指标进行分析比较。结果老年MS组与单纯老年高血压组比较:MS组的夜间平均收缩压(nMSP)、24h平均脉压高于单纯高血压组(P<0.01或P<0.05),昼夜收缩压和舒张压差值低于单纯高血压组(P<0.01)。伴靶器官损害MS组与单纯MS组比较:伴靶器官损害MS组白昼平均收缩压(dMSP)、nMSP、24h平均脉压较单纯MS组增高(P<0.05或P<0.01),24hMDP、dMDP、nMDP较单纯MS组降低(P<0.05)。结论血压的昼夜差值与MS,脉压与MS及靶器官损害程度关系密切。
Objective To investigate the relationship between 24h ambulatory blood pressure and 24h pulse pressure and its target organ damage in elderly patients with metabolic syndrome (MS). Methods Ninety-two elderly hypertensive patients, 88 elderly patients with simple MS and 117 elderly MS patients with target organ damage were analyzed for ambulatory blood pressure monitoring. Results The mean nocturnal mean systolic blood pressure (nMSP), mean systolic blood pressure (24h) in MS group were significantly higher than those in simple hypertension group (P <0.01 or P <0.05), and systolic and diastolic blood pressure Value was lower than simple hypertension group (P <0.01). Compared with the MS group, the mean daytime pulse pressure (nMSP) and mean arterial pressure (24h) in MS group were significantly higher than those in MS group (P <0.05 or P <0.01), 24hMDP and dMDP , NMDP than the simple MS group decreased (P <0.05). Conclusion The difference of day and night blood pressure is closely related to the severity of MS, pulse pressure, MS and target organ damage.