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血小板是血液中最小的有形成分,但是它在动物及人体中却有极重要的生理功能。近几年来人们认识到,血小板除参与止血和血栓形成外,还与维持血管内皮的完整性有关,并参与创伤愈合、动脉粥样硬化、肿瘤转移、炎症以及移植排斥等多种生理及病理过程,因而有多功能细胞之称。近年出现的抗血小板疗法,把多种抑制血小板活性的药物用于临床治疗或预防动脉粥样硬化,预防血栓形成,均取得了满意的效果。检测血小板功能的技术、方法也在不断提高。本文在这方面作扼要介绍。
Platelets are the smallest of the visible components of blood, but they have extremely important physiological functions in animals and humans. In recent years, people have realized that in addition to participating in hemostasis and thrombosis, platelets are also involved in maintaining the integrity of the vascular endothelium and are involved in various physiological and pathological processes such as wound healing, atherosclerosis, tumor metastasis, inflammation, and transplant rejection , So there is a multi-functional cell called. In recent years, the emergence of anti-platelet therapy, a variety of drugs that inhibit platelet activity for clinical treatment or prevention of atherosclerosis, prevention of thrombosis, have achieved satisfactory results. Detection of platelet function of the technology, methods are also continuously improve. This article gives a brief introduction in this regard.