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目的评估宫颈环形电切术(LEEP)后妊娠的流产风险,并评估其与LEEP至妊娠时间间隔之间的相关性。方法选取2007年1月-2014年12月行LEEP后妊娠的患者为实验组,选取同期因巴氏涂片见不明意义的非典型鳞状细胞(组织学评估为宫颈低度病变,无需宫颈切除或消融术)行阴道镜检查的患者为对照组。通过查找病历和电话随访收集患者的妊娠时间、妊娠周数、妊娠结局和终止妊娠方式等资料。结果在LEEP至妊娠时间间隔<12个月的患者中,流产率显著升高,而在LEEP至妊娠时间间隔≥12个月的患者中,流产率与对照组比较差异无统计学意义(P>0.05)。结论这些发现可能帮助提供LEEP术后妊娠的最佳时机,以减少流产的风险。
Objective To assess the risk of miscarriage during pregnancy after cervical torotomy (LEEP) and to assess its association with LEEP to gestational time. Methods From January 2007 to December 2014, patients undergoing post-LEEP pregnancy were selected as the experimental group. Atypical squamous cells of unknown significance due to Pap smears were selected (histologically assessed as low-grade cervical lesions without cervical resection Or ablation) colposcopy patients for the control group. The patient’s pregnancy time, the number of weeks of pregnancy, the outcome of pregnancy and the way of termination of pregnancy were collected by searching medical records and telephone follow-up. Results The rate of miscarriage increased significantly between LEEP and gestational age <12 months, while there was no significant difference in miscarriage rate between control group and LEEP until the age of 12 months or more (P> 0.05). Conclusions These findings may help provide the best timing for post-LEEP pregnancy to reduce the risk of miscarriage.