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地中海贫血地中海贫血包括一组性质类似的遗传性溶血性疾病,其共同特点为珠蛋白中某种正常肽链的合成减少或缺如,导致血红蛋白成分的改变和数量减少,并由此而产生一系列的临床表现。本病分布很广,以地中海沿岸和东南亚国家居民的发病率最高。我国广东和广西为本病的高发区,四川、西藏、福建、浙江、江苏、贵州、江西、湖北、宁夏等省(区)亦有病例报导。本病在我国主要分为两型:1.β肽链合成减少者,称为β地中海贫血;2.α肽链合成减
Thalassemia Thalassemia includes a group of hereditary hemolytic disease of similar nature that is characterized by a diminished or absent synthesis of a normal peptide chain in globin leading to a change and a decrease in the amount of hemoglobin and resulting in a Series of clinical manifestations. The disease is widely distributed to residents of the Mediterranean coast and Southeast Asian countries the highest incidence. Cases of high incidence of this disease are found in Guangdong and Guangxi in our country. Cases have also been reported in Sichuan, Tibet, Fujian, Zhejiang, Jiangsu, Guizhou, Jiangxi, Hubei and Ningxia provinces. The disease is divided into two types in our country: 1. P-peptide synthesis reduced, known as β-thalassemia; 2.α peptide synthesis by