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本文作者采用双盲、安慰对照、平衡研究方法,评价了阿普唑仑(Alprazolam)对特发性震颤(ET)的疗效。方法:将24例ET患者随机分为阿普唑仑组(12例)、安慰剂组(12例)。阿普唑仑的开始剂量为0.25mg,每日3次,允许每天增加0.25mg,至每天最大剂量为3mg,用药2周。结果:临床等级评价提示,与基础等级相比,治疗组震颤的严重程度显著改善(P<
The authors evaluated the efficacy of alprazolam in patients with idiopathic tremor (ET) using a double-blind, comfort-controlled, balanced study. Methods: 24 patients with ET were randomly divided into alprazolam group (12 cases) and placebo group (12 cases). Alprazolam starting dose of 0.25mg, 3 times a day, allowing an increase of 0.25mg daily to a maximum daily dose of 3mg, medication for 2 weeks. Results: Clinical grade evaluation suggested that the severity of tremor in the treatment group was significantly improved compared with the baseline grade (P <