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目的分析住院患者2014年质子泵抑制剂(PPIs)使用情况,为临床合理使用PPIs提供参考。方法从河南医学高等专科学校附属医院计算机信息系统提取2014年住院患者使用PPIs的信息,包括药品名称、规格、剂型、用量、销售金额等,同时获取2014年住院总人数及平均住院日,计算使用强度、日均费用、用药频度;随机抽取2014年住院患者使用PPIs病历,评价其合理性。结果全年住院患者PPIs使用强度是64.19,DDC是38.04,使用频度最高的是泮托拉唑注射剂;600份PPIs使用病历中不合理使用62.33%。结论 PPIs使用严重不合理,应加强提高医生对PPIs的认识,严格掌握PPIs使用指征,加强药师对处方的审核,杜绝不合理使用PPIs的发生。
Objective To analyze the use of proton pump inhibitors (PPIs) in hospitalized patients in 2014 and provide a reference for the rational use of PPIs in clinic. Methods The information of inpatients using PPIs in 2014 was extracted from the computerized information system of Affiliated Hospital of Henan Medical College, including the names, specifications, dosage forms, dosage and sales amount of the drugs, and the total length of stay and average length of stay in 2014 were calculated and used Intensity, daily average cost and frequency of medication. Randomized 2014 inpatient use of PPIs medical records, evaluation of its rationality. Results The annual inpatient PPIs intensity was 64.19, DDC was 38.04, and the highest frequency of use was pantoprazole injection. Sixty-three PPIs were used illegitimately in the medical records of 62.33%. Conclusion The use of PPIs is serious and unreasonable. It is necessary to strengthen the doctors’ understanding of PPIs, strictly control the indications of using PPIs, strengthen the examination of prescriptions by pharmacists, and prevent the occurrence of unreasonable use of PPIs.