周期素依赖性激酶是与细胞周期相关的细胞周期蛋白——周期素依赖性激酶——周期素依赖性激酶抑制物网络调节系统中的中心环节 ,它在细胞周期调控中异常 ,与肿瘤的发生密切相关。对于 Cdk的生物学特性 ,作用机制及其检测在肿瘤学研究、诊断、治疗以及其预后观察中都有十分重要的价值。本文对细胞周期、Cdk网络调节系统与细胞周期的关系、Cdk系统与肿瘤发生、发展的关系作了综述 Cyclin-dependent kinase is a central link in cell cycle-related cyclin-cyclin-dependent kinase, a cyclin-dependent kinase inhibitor network regulation system. It is abnormal in cell cycle regulation and tumorigenesis. closely related. For the biological characteristics of Cdk, the mechanism of action and its detection have very important value in oncological research, diagnosis, treatment and observation of its prognosis. This article reviews the relationship between cell cycle, the relationship between Cdk network regulatory system and cell cycle, and the relationship between Cdk system and tumorigenesis and development.