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4-氨基水杨酸(4-ASA)(又称对氨基水杨酸)是一种可大剂量用于治疗结核的较安全药物,属5-氨基水杨酸(5-ASA)的一种同分异构体。5-ASA目前用于治疗中度活动克隆病及活动性溃疡性结肠炎。由于4-ASA比5-ASA更稳定且有与5-ASA相当的抗炎作用,本文对一组静止期克隆回结肠炎病人作双盲、随机比较研究口服肠溶性4-ASA与5-ASA各1.5g/d
4-Aminosalicylic acid (4-ASA), also known as p-aminosalicylic acid, is a safer drug that can be used in large doses to treat tuberculosis and is a 5-aminosalicylic acid (5-ASA) Isomers. 5-ASA is currently used to treat moderately active Crohn’s disease and active ulcerative colitis. Since 4-ASA is more stable than 5-ASA and has comparable anti-inflammatory effects to 5-ASA, a randomized, double-blind, randomized, comparative study of a group of patients with colony-forming colonitis returned to oral administration of 4-ASA and 5-ASA Each 1.5g / d