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严重的职业性铅中毒可引起肾小管功能障碍,但临床常用的肾功能试验尚欠灵敏,不能检出早期肾小管损害。据报道尿N-乙酰基β-氨基葡萄糖苷酶(NAG)可作为检测肾小管功能障碍的一个早期指标。本文选用尿NAG等指标,对某再生铅熔炼厂46名工人进行肾功能检查,并分析尿NAG活性和铅接触指标的关系,以探讨引起肾小管功能障碍的铅接触水平。研究对象:铅精炼厂工人男39人,年龄17～72岁,平均51.1岁,工龄0.1～40年,平均10.5年;女7人,年龄20～68岁,平均
Serious occupational lead poisoning can cause renal tubular dysfunction, but the clinical renal function tests are still not sensitive, can not detect early tubular damage. Urinary N-acetyl-glucosaminidase (NAG) has been reported as an early marker of renal tubular dysfunction. In this paper, urinary NAG and other indicators, a recycled lead smelter 46 workers renal function tests and analysis of urinary NAG activity and lead exposure to indicators, to explore the cause of renal tubular lead exposure levels. Research object: Lead refinery workers, 39 men, aged 17 to 72 years, mean 51.1 years, length of service 0.1 to 40 years, an average of 10.5 years; 7 women, aged 20 to 68 years, mean