1961年 Jordan 曾首先报告1例服用避孕药后发生肺血栓形成,此后在文献上已报告数百例因服此药而发生肺血栓形成或增殖性血栓静脉炎者。有关的研究工作正分三方面进行,即统计分析,实验研究及临床病例报告;但均未有很成熟的论证。Lorentz 曾指出:口服避孕药可能与脑血管病有关,但未引起人们注 In 1961, Jordan first reported pulmonary thrombosis after taking a pill. Since then, hundreds of cases of pulmonary thrombosis or proliferative thrombophlebitis have been reported in the literature. Relevant research work is being conducted in three aspects, namely, statistical analysis, experimental studies and clinical case reports; however, none of them has been well-established. Lorentz has pointed out: oral contraceptives may be related to cerebrovascular disease, but did not attract people’s attention