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目的探讨骨髓活检和骨髓涂片在血液病诊断中的意义。方法对650例血液病患者,分别进行外周血采集,骨髓活检和骨髓穿刺,分别观察骨髓涂片和骨髓活检切片。结果骨髓活检切片能准确地反映骨髓细胞增生程度,对恶性细胞的检出率更高。在淋巴瘤、骨髓纤维化、骨髓增生异常综合征、骨髓转移癌、多发性骨髓瘤诊断方面,骨髓活检优于涂片。结论骨髓活检和涂片同步观察能有效提高血液病的诊断率,减少误诊率,并正确判断疾病的分期。
Objective To investigate the significance of bone marrow biopsy and bone marrow smear in the diagnosis of hematological diseases. Methods Peripheral blood samples, bone marrow biopsy and bone marrow aspiration were performed on 650 patients with hematologic diseases. Marrow smears and bone marrow biopsy sections were observed. Results Bone marrow biopsy can accurately reflect the degree of bone marrow cell proliferation, the detection rate of malignant cells higher. In lymphoma, myelofibrosis, myelodysplastic syndrome, bone marrow metastases, multiple myeloma diagnosis, bone marrow biopsy better than smears. Conclusion The simultaneous observation of bone marrow biopsy and smear can effectively improve the diagnostic rate of blood diseases, reduce the misdiagnosis rate, and correctly determine the stage of the disease.