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目的 :观察外照射 +腔内放疗对鼻咽癌原发灶复发的治疗效果 ,分析可能影响结果的因素。方法 :1988年12月至 1994年 11月 ,收治经根治性放疗后腔内复发的鼻咽癌共 73例 ,采用外照射 +腔内放疗。结果 :总的 5年生存率、无瘤生存率、局控率分别是 2 0 .7%、17.8%、41.1%。分析了治疗总剂量及外照射剂量对生存率的影响。结论 :外照射 +腔内放疗对鼻咽癌腔内复发是一种有价值的方案。外照射 +腔内放疗总剂量不低于 5 6 GY,外照射应在42 GY以上。
Objective: To observe the therapeutic effect of external beam radiotherapy and intracavitary radiotherapy on the recurrence of primary nasopharyngeal carcinoma and analyze the factors that may affect the result. Methods: From December 1988 to November 1994, a total of 73 cases of nasopharyngeal carcinoma after radical radiotherapy were treated with endovascular radiotherapy. External beam radiotherapy and intracavitary radiotherapy were used. Results: The overall 5-year survival rate, tumor-free survival rate and local control rate were 20.7%, 17.8% and 41.1% respectively. The effect of total dose and external dose on the survival rate was analyzed. Conclusion: External irradiation + intracavitary radiotherapy for nasopharyngeal carcinoma cavity recurrence is a valuable program. The total dose of external radiation + intracavitary radiotherapy is not less than 56 GY and the external radiation should be above 42 GY.