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本文综述了放射免疫分析对血液病诊断的若干进展。血中β2m<或>6μg/ml 是 MM 选择简单或强烈诱导化疗的分界线。N-HD 和 HD 血清β2m 增高。恶性淋巴瘤、慢性髓细胞白血病和急性白血病的铁蛋白/铁比值明显高于正常人。FⅦ各成份的检测,可作为 vWD 诊断和分型的依据之一。DIC 和血栓性疾病时 AT-Ⅲ水平降低,如果结合生物学测定,可具有早期预测静脉血栓的价值。白血病患者血浆和尿中 cGMP 水平显著增高,cAMP/cGMP 克分子比值降低。有高度血管血栓形成危险的 PV 患者,多数存在着β-TG 和 PF-4的增高。
This article reviews several advances in the diagnosis of hematological diseases by radioimmunoassay. Blood β2m 6μg / ml is the choice of simple or strong induction of chemotherapy in MM boundaries. N-HD and HD serum β2m increased. The ratios of ferritin / iron in malignant lymphoma, chronic myelogenous leukemia and acute leukemia were significantly higher than those in normal people. FⅦ detection of each component, vWD diagnosis and typing can be used as a basis. AT-III levels are reduced in DIC and thrombotic conditions, and may be of value in predicting venous thrombosis early if combined with biological assays. Patients with leukemia in plasma and urine cGMP levels were significantly higher, cAMP / cGMP molar ratio decreased. PV patients with a high risk of vascular thrombosis, the majority of the presence of β-TG and PF-4 increased.