口腔癌在常见肿瘤中位于第6位,经过过去几十年的发展,手术,放疗及化疗并没有显著提高口腔癌患者的生存率,并且术后患者的生活质量普遍下降;因此早期诊断是提高患者生存率和生存质量的关键。随着后基因组时代的到来,系统生物学逐渐受到关注,将系统生物学应用于肿瘤领域是目前的研究热点。本文简要介绍了目前系统生物学技术在口腔癌诊断中的应用进展。 Oral cancer is located at the 6th in the common tumor. After decades of development, surgery, radiotherapy and chemotherapy did not significantly improve the survival rate of oral cancer patients, and the quality of life of postoperative patients generally declined; therefore, the early diagnosis is increased The key to patient survival and quality of life. With the advent of the post-genomic era, more attention has been paid to systematics and biology. It is currently a hot research topic to apply Systematic Biology in the field of oncology. This article briefly introduces the current application of system biology in the diagnosis of oral cancer.