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转化生长因子β１（Ｔｔｒａｎｓｆｏｒｍｉｎｇｇｒｏｗｔｈｆａｃｔｏｒβ１，ＴＧＦβ１）是一种具有广泛生物学作用的同源二聚体多肽。它可在细胞增殖、细胞外基质沉积、血管生成及免疫反应等生理病理过程中起作用［１］。其在肿瘤发生和恶性转化过程中的作用尤其受到有关
Transforming growth factor β1 (TGFβ1) is a homodimeric polypeptide with a wide range of biological effects. It plays a role in the physiological and pathological processes such as cell proliferation, extracellular matrix deposition, angiogenesis and immune response [1]. Its role in tumorigenesis and malignant transformation is particularly relevant