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目的 观察卡前列甲酯用于预防产后出血的效果。方法 选择 2 0 2例足月妊娠阴道分娩产妇 ,随机分为卡前列甲酯组和缩宫素组。卡前列甲酯组 10 2例 ,于胎儿娩出后立即向直肠内置入卡前列甲酯栓 1粒 (含 1mg)。缩宫素组10 0例 ,5 0例于胎儿娩出后肌注缩宫素 10u ,另 5 0例静脉静缩宫素 2 0u ,观察产后 2h的出血量及第三产程。结果 卡前列甲酯组产后 2h平均出血量 ( 181 3± 7 7)ml ,肌注缩宫素组 ( 2 2 6.0± 12 9 8)ml,静脉点滴缩宫素组 ( 2 15 7± 93 3 )ml ,卡前列甲酯组与缩宫素组比较差异有显著性 (P <0 0 5 )。第三产程 ,卡前列甲酯组 ( 6 7± 3 8)min ,肌注缩宫素组 ( 10 7±5 5 )min ,静脉点滴缩宫素组 ( 10 4± 4 8)min ,卡前列甲酯组与缩宫素组比较差异有显著性 (P <0 0 5 )。结论 卡前列甲酯具有较缩宫素更强的缩宫作用且用药方便
Objective To observe the effect of methyl palmitate on preventing postpartum hemorrhage. Methods 220 cases of vaginal delivery of full-term pregnant women were randomly divided into card before methyl ester group and oxytocin group. Card forefront of the methyl ester group 102 cases, immediately after the delivery of the fetus into the rectum into the card forefront of methyl ester suppositories 1 (containing 1mg). Oxytocin group of 10 cases, 50 cases of intrauterine injection of oxytocin 10u, another 50 cases of intravenous oxytocin 20u, observation of postpartum 2h bleeding and the third stage of labor. Results The average amount of bleeding at 2h after birth was (181 3 ± 7 7) ml in the card methylester group, (22 6.0 ± 12 9 8) ml in the oxytocin group, and 2 15 7 ± 93 3 in the intravenous injection oxytocin group ) ml, there was a significant difference between the methylester group and oxytocin group (P <0.05). The third trimester of labor were as follows: cardioprotective group (67 ± 38) min, intramuscular oxytocin group (107 ± 55) min, intravenous oxytocin group (104 ± 48) min, Methyl ester group and oxytocin group was significantly different (P <0 05). Conclusions Cardinal methylester has a stronger contraction effect than oxytocin and is convenient for medication