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在自行研制的高压静电成囊装置上进行了制备微胶囊的试验研究. 以海藻酸钠在氯化钙中固化成囊方法,进行了平针头与斜针头的成囊电压、跳火电压对比试验研究,得出平针头优于斜针头的结果;分析了电压、推进速度、液面距等参数变化对制成的微胶囊直径和均匀度的影响;对于1.5%的海藻酸钠溶液和7# 平针头,得到满足胰岛细胞团微胶囊化要求的较佳参数组合为电压5kV,推进速度50mm/h,液面距20mm.
In the self-developed high-voltage electrostatic capsule device for the preparation of microcapsules experimental study to sodium alginate in calcium chloride into the capsule method, the flat needle and oblique needle capsule voltage, flashover voltage comparison test The effects of the parameters such as voltage, propulsion velocity and liquid surface distance on the diameter and uniformity of microcapsules were analyzed. For 1.5% sodium alginate solution and 7 # Flat needle, to meet the microencapsulation of islet cell mass of the better combination of parameters for the voltage 5kV, advancing speed 50mm / h, the liquid surface distance 20mm.