目的　探讨高血压病患者的左心室构型及功能改变与临床分期的关系。方法　按照世界卫生组织对高血压病诊断分期标准 ,选择高血压病Ⅰ期组 2 0例 ,Ⅱ期组 3 0例 ,Ⅲ期组 3 0例 ,进行常规二维 ,M型及彩色和频谱多普勒超声检查。按照美国超声心动图学会 (ASE)推荐的前缘至前缘法测量室间隔厚度 (IVST) ,左室后壁厚度 (PWT) ,左室舒张期前后径 (LVDd) ,根据Devereux校正公式计算左心室心肌重量 (LVM)。测定左室收缩功能指标射血分数 (LVEF) ,短轴缩短率 (LVFS)。用脉冲多普勒测定舒张期二尖瓣口血流峰值速度Ev和Av ,计算E/A比值。所有数据用统计学处理。结果　LVDd测定 ,Ⅰ期组 (4 5 8± 0 3 7)cm ,Ⅱ期组 (4 85±0 5 7)cm ,Ⅲ期组 (5 3 5± 0 71)cm。LVM计算 ,Ⅰ期组 (175 41± 2 1 5 7)g ,Ⅱ期组 (2 2 6 67± 3 5 3 1)g ,Ⅲ期组 (2 90 0 0± 5 0 2 4)g。LVEF %测定 ,Ⅰ期组 65 12± 5 78,Ⅱ期组 68 5 1± 6 3 5 ,Ⅲ期组 5 1 3 5± 4 82。E/A比值 ,Ⅰ期组 1 1,Ⅱ期组 0 87,Ⅲ期组 0 69。结论　 1、高血压病患者的左室心肌重量随着临床分期的加重而明显增加 ,左心室内径逐渐扩大 ,LVM、LVDd与高血压病分期为正比相关 ,Ⅰ期<Ⅱ期 <Ⅲ期。 2、高血压病患者左室舒张功能随着临床分期的加重而减低 Objective To investigate the relationship between left ventricular configuration and functional changes and clinical stage in patients with essential hypertension. Methods According to World Health Organization (WHO) staging criteria for hypertension, 20 cases of stage Ⅰ, 30 cases of stage Ⅱ and 30 cases of stage Ⅲ were selected. Pulsed ultrasound. The left ventricular posterior wall thickness (PWT) and left ventricular diastolic anteroposterior diameter (LVDd) were measured according to the ASE recommended front-to-front-edge method and the left Ventricular Myocardial Weight (LVM). Left ventricular systolic function ejection fraction (LVEF), short axis shortening (LVFS) were measured. Pulse wave Doppler was used to measure the peak velocity of diastolic mitral inflow Ev and Av, and the E / A ratio was calculated. All data were statistically processed. Results The LVDd in group Ⅰ was (45 58 ± 0 37) cm, in group Ⅱ (4 85 ± 0 57) cm, and in group Ⅲ (53 5 ± 0 71) cm. In the LVM group, there were no significant difference between the two groups (175 41 ± 2157) in group Ⅰ, group Ⅱ (22.66 ± 3.531) g and group Ⅲ (2 90 0 ± 5 024) g. LVEF%, 65 12 ± 5 78 in stage Ⅰ, 68 5 1 ± 6 3 5 in stage Ⅱ, and 5 1 3 5 ± 4 82 in stage Ⅲ. The ratio of E / A, stage Ⅰ 1 1, stage Ⅱ 0 87, stage Ⅲ 0 69. LVMI and LVDd were positively correlated with the stages of hypertension, and stage Ⅰ <Ⅱ