目的探讨中药联合腔内化疗配合尿激酶治疗恶性包裹性胸腔积液的临床疗效。方法将近期本院收治的80例恶性包裹性胸腔积液患者作为研究对象,80例患者随机分为试验组(40例)和对照组(40例)。对照组采用单纯腔内化疗配合尿激酶方法治疗,试验组采用中药联合腔内化疗配合尿激酶方法治疗,观察比较两组患者的临床治疗效果。结果试验组治疗后的总有效率明显高于对照组(P<0.05);治疗期间两组患者的生活质量比较差异具有统计学意义(P<0.05);试验组患者不良反应发生率明显低于对照组(P<0.05)。结论采用中药联合腔内化疗配合尿激酶治疗恶性包裹性胸腔积液效果显著,并不良反应少,值得推广应用。 Objective To investigate the clinical efficacy of combined traditional Chinese medicine and endovascular chemotherapy with urokinase in the treatment of malignant pleural effusion. Methods Eighty patients with malignant pleural effusion admitted in our hospital were enrolled in this study. Eighty patients were randomly divided into experimental group (40 cases) and control group (40 cases). The control group was treated with simple intracavitary chemotherapy and urokinase. The experimental group was treated with traditional Chinese medicine combined with lumen chemotherapy and urokinase, and the clinical effects of the two groups were observed and compared. Results The total effective rate of the experimental group after treatment was significantly higher than that of the control group (P <0.05). There was significant difference in quality of life between the two groups during the treatment (P <0.05). The incidence of adverse reactions in the experimental group was significantly lower than that of the control group Control group (P <0.05). Conclusion The combination of traditional Chinese medicine and endovascular chemotherapy with urokinase in the treatment of malignant pleural effusion is effective and has few adverse reactions. It is worth popularizing and applying.