本文分析了固紫阴性杆菌脑膜炎61例。这些病例占1968～1973年全部细菌性脑膜炎的4.2％,其中35例为神经外科手术后患者,19例为新生儿,总的病死率为40.3％。在一岁以下的患者所分离出的致病菌以大肠杆菌为最常见,而一岁以上的则以肺炎杆菌属为主。作者认为,固紫阴性杆菌脑膜炎通常是一种医源性感染,主要见于神经外科患者和新生儿。在该院神经外科手术后脑膜炎的总发病率是0.5％,其中69％是由固紫阴性杆菌引起的。而在新生儿中,固紫阴性 In this paper, 61 cases of solid-violet-negative bacillus meningitis were analyzed. These cases accounted for 4.2% of all bacterial meningitis from 1968 to 1973, of which 35 were neurosurgical patients and 19 were neonates with a total case fatality rate of 40.3%. Escherichia coli is the most common pathogen isolated in patients under one year of age, while Klebsiella spp. Predominates in individuals over the age of one. The author believes that solid-violet-negative bacillus meningitis is usually a iatrogenic infection, mainly seen in neurosurgical patients and newborns. The overall incidence of meningitis after neurosurgery in the hospital was 0.5%, of which 69% was caused by C18-negative bacilli. In newborns, solid purple negative