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本文报告15例CO中毒迟发脑病,主要临床特征是近1～2个月有明确的CO中毒昏迷史,经数日至数周间歇期后出现精神症状。主要表现为行为紊乱、欣快诙谐、精神错乱和痴呆性神游症。脑电图显示两半球弥漫性慢波。本组病例采用以高压氧为主的综合疗法,治愈9例,好转5例,无效1例。总有效率为93.3％。本文对其发病机理、脑电图检查价值、预后与开始高压氧治疗时间及疗次的关系等提出了我们的初步看法。
This article reports 15 cases of CO poisoning delayed encephalopathy, the main clinical features of nearly 1 ~ 2 months have a clear CO poisoning coma history, after a few days to several weeks after the break to the emergence of mental symptoms. Mainly manifested as behavioral disorders, euphoria, delirium and dementia fugue. EEG shows diffuse slow wave in both hemispheres. This group of patients with hyperbaric oxygen-based combination therapy, 9 cases were cured, improved in 5 cases, 1 case of ineffective. The total effective rate was 93.3%. This article put forward our preliminary view on its pathogenesis, the value of EEG examination, the relationship between prognosis and the time and treatment of hyperbaric oxygen therapy.