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１９９２年，Ｓａｓａｎｏ等［１］采用ＰＡｂ１８０１单克隆抗体在４％多聚甲醛固定的冰冻切片中发现１２例呈阳性，阳性率达８０％，并认为核内ｐ５３蛋白的显示提示为突发型。我国北方是食管癌的高发区，而在南方其发生率较低。本文着重探讨高、低发区食管癌中ｐ５３蛋...
In 1992, Sasano et al [1] used PAb1801 monoclonal antibody to detect 12 cases positive in 4% paraformaldehyde fixed frozen sections, and the positive rate was 80%. It is considered that the display of nuclear p53 protein in the nucleus is abrupt. North China is a high-risk area of esophageal cancer, and its incidence is lower in the south. This article focuses on the high and low incidence of esophageal cancer p53 eggs ...