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将28只生长期大鼠随机分为对照组、服锰组和腹腔注锰组。结果表明,给锰途径不影响大鼠组织的总体锰、硒分布,却可不同程度地影响组织的锰、硒含量和 GSH-PX 活性,注锰后,使全血、心、肝、肾组织的锰含量显著升高,全血和肝组织的硒含量和 GSH-PX 活性降低;服锰后,可使组织的锰有所增高,却未达到引起统计学和生物学效应的水平,而食入的锰几乎完全地从粪便中排出。
The 28 growing rats were randomly divided into control group, serving manganese group and peritoneal injection of manganese group. The results showed that the administration of manganese did not affect the distribution of total manganese and selenium in rat tissues, but could affect the contents of manganese, selenium and GSH-PX in tissues to varying degrees. After manganese injection, whole blood, heart, liver and kidney tissues Of manganese content increased significantly, whole blood and liver tissue selenium content and GSH-PX activity decreased; serving manganese, can make tissue manganese increased, but did not reach the level of statistical and biological effects, and food Manganese is discharged almost completely from the excrement.