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目的 探讨C erbB 2癌基因与腺癌的关系 .方法 采用核酸分子杂交技术、PCR法、免疫组化 .结果 C erbB 2扩增或过度表达广泛存在于人的各种腺癌细胞 .结论 C erbB 2基因与腺癌的发生、分化、恶性程度、转移及预后有着密切的关系 .
Objective To investigate the relationship between C erbB 2 oncogene and adenocarcinoma.Methods Hybridization of nucleic acid molecules, PCR and immunohistochemistry were performed.Results C erbB 2 was widely expressed in human adenocarcinoma cells.Conclusion C erbB 2 gene and adenocarcinoma of the occurrence, differentiation, malignancy, metastasis and prognosis are closely related.