论文部分内容阅读
目的探讨心得安对诊所高血压病患者转变为真性高血压病及造成靶器官损害、发生心血管事件几率的影响。方法 73例诊所高血压病患者随机分为两组,一组为治疗组(37例,应用心得安10 mg,3次/d,口服),一组为对照组(36例,给予安慰剂口服,给药方法同治疗组),连续观察3年。结果治疗组有1例发展为真性高血压病,无靶器官损害或心血管事件发生;对照组有8例发展为真性高血压病,有4例发生靶器官损害,有2例心血管事件发生(其中腔隙性脑梗死1例,一过性脑缺血发作1例)。结论心得安能减少诊所高血压病患者发展为真性高血压病及造成靶器官损害或心血管事件发生的几率。
Objective To investigate the effect of Triad on the patients with hypertension in clinic and change the cause of target organ damage and the incidence of cardiovascular events. Methods A total of 73 clinic patients with hypertension were randomly divided into two groups. One group was treated group (37 cases, application of propranolol 10 mg, 3 times / d orally), one group as control group (36 cases, placebo oral administration , The same method of treatment with the treatment group), continuous observation for 3 years. Results In the treatment group, 1 patient developed true hypertension without target organ damage or cardiovascular events. In the control group, 8 patients developed true hypertension, 4 had target organ damage and 2 had cardiovascular events (1 case of lacunar infarction and 1 case of transient ischemic attack). Conclusions Enzamine reduces the risk of developing hypertensive disorders and causing target organ damage or cardiovascular events in clinically hypertensive patients.