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目的通过应用美托洛尔缓释片治疗慢性充血性心力衰竭(CHF)，以评价美托洛尔的疗效。方法120例慢性心力衰竭患者，将其随机分配成治疗组、对照组，各60例。对照组进行常规治疗，治疗组在前者基础上增加美托洛尔缓释片47.5mg，1次/d，在随后时间里逐渐加量到142.5mg。结果治疗组猝死率明显减低，治疗后射血分数(EF)较对照组明显增加，室性心律失常明显减少。结论美托洛尔缓释片可增加慢性心力衰竭患者EF，减少室性心律失常。“,”Objective To explore the ef ect of metoprolol tartrate sustained release tablets in treatment of Congestive Heart Failure (CHF).Methods 120 patients with CHF were randomly divided into two groups:treatment group and control group,with each 60 case.Based on the conventional treatment,the patients in the treatment group were given metoprolol tartrate sustained release tablets (47.5mg qd), increasing the dosage up to 142.5mg qd or the patients”, maximum tolerated dose.The patients in the control group were given other treatment.Results After treatment with metoprolol tartrate sustained release tablets for 6 months,the treatment group had lower rate of sudden death,high EF.Conclusion Metoprolol tartrate sustained release tablets can increase the ejection fraction,reduce the ventricular arrhythmia.