目的观察液氮冷冻治疗复发性口腔溃疡的疗效。方法将170例口腔溃疡患者随机分为治疗组和对照组各85例。治疗组采用液氮冷冻并辅以中药“口疮液”漱服治疗;对照组单纯用中药“口疮液”漱服治疗。结果治疗组痊愈和显效率74.1%,对照组率仅64.7%(P<0.05);治疗组疗效较佳。结论液氮冷冻治疗口腔溃疡可明显提高疗效,且缩短病程,减轻临床症状。 Objective To observe the effect of liquid nitrogen cryotherapy on recurrent oral ulcer. Methods 170 patients with oral ulcer were randomly divided into treatment group and control group of 85 cases. The treatment group was treated with liquid nitrogen freezing supplemented with traditional Chinese medicine “aphthous solution” and the control group was treated with traditional Chinese medicine “aphthous solution” only. Results In the treatment group, the cure rate was 74.1% and the control group was only 64.7% (P <0.05). The treatment group had better curative effect. Conclusion Liquid nitrogen cryogenic treatment of oral ulcers can significantly improve the efficacy, and shorten the course of disease, reduce clinical symptoms.