骨钙素(Osteocalcin)是骨基质中含量最高的非胶元蛋白.正常情况下,血清骨钙素水平与成骨有关,已有报道多发性骨髓瘤病人骨钙素与骨形成的组织学参数密切相关.本文报道多发性骨髓瘤病人就诊时血清骨钙素水平与病期及生存期的关系.48例病人在治疗前作了血清骨钙素测定,所有病人均排除影响骨钙素水平的因素.病人年龄38～83岁,中位数66岁,男女之比为2∶1,其中IgG 型 Osteocalcin is the most abundant non-collagen protein in bone matrix. Under normal circumstances, serum osteocalcin levels are related to osteogenic, and the histological parameters of osteocalcin and bone formation in patients with multiple myeloma have been reported. Closely related. This article reports the relationship between serum osteocalcin levels and disease stage and survival time in multiple myeloma patients. 48 patients were measured serum osteocalcin before treatment, and all patients excluded factors that affect the level of osteocalcin. The patient’s age ranged from 38 to 83 years with a median of 66 years. The ratio of male to female was 2:1, of which IgG type