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目的 了解过敏原过筛试验在婴幼儿哮喘中的临床意义。方法 对78例确诊为婴幼儿哮喘患儿行CAP过敏原检测系统中的吸入性过敏原过筛Phadiatop试验和食物过敏原过筛Fx5E 试验并与传统的过敏原诊断方法皮肤试验相比较。结果 (1)过敏因素是婴幼儿哮喘的一个重要因素,有53.8%患儿血清Fx5E阳性,有36.8%患儿血清Phadiatop阳性。(2)Phadiatop的阳性率明显高于皮肤点刺试验,经X2检验,两种方法的阳性率有显著性差异(X2=4.65, P<0.05)(3)婴幼儿哮喘患儿中食物IgE的阳性率比吸入IgE的阳性率更高。结论 过敏因素是婴幼儿哮喘的一个重要因素;婴幼儿哮喘患儿中食物过敏情况比吸入物过敏更重要;Phadiatop试验和Fx5E试验是一项简便、可靠的过敏原过筛试验。
Objective To understand the clinical significance of allergen screening test in infant asthma. Methods 78 children diagnosed as infants and young children with asthma in children with allergen detection system of allergen inhalation allergen screening Phadiatop test and food allergen screening Fx5E test and compared with the traditional method of allergen skin test. Results (1) Allergic factor is an important factor in infant asthma. Fx5E was positive in 53.8% of the children and positive in 36.8% of the children with Phadiatop. (2) The positive rate of Phadiatop was significantly higher than that of the skin prick test. The positive rates of the two methods were significantly different (X2 = 4.65, P <0.05) by X2 test. (3) The positive rate is higher than the positive rate of inhaled IgE. Conclusions Allergic factors are an important factor in infant asthma. Food allergy in infants and young children is more important than inhalation allergy. Phadiatop and Fx5E tests are simple and reliable allergen screening tests.