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目的 :探讨刺五加对蛛网膜下腔出血 ( SAH)患者血清 NO水平的影响。方法 :动态观察常规治疗组和刺五加治疗组发病后第 2、4、6天血清中 NO的水平 ,并与正常对照组比较。结果 :发病后第 4、6天常规治疗组和刺五加治疗组病人血清 NO水平明显低于对照组 ( P<0 .0 1,P<0 .0 5 ) ,第 4天下降达低谷 ,第 6天又逐渐回升。轻症组与重症组血清 NO水平降低不明显 ( P>0 .0 5 )。结论 :刺五加制剂对 SAH后继发性脑损害可能有防治作用
Objective: To investigate the effect of Acanthopanax senticosus on serum NO level in patients with subarachnoid hemorrhage (SAH). Methods: The levels of NO in serum of routine treatment group and Acanthopanax senticosus group were observed dynamically on the 2nd, 4th and 6th day after onset, and compared with the normal control group. Results: The levels of serum NO in the routine treatment group and Acanthopanax senticosus treatment group were significantly lower than those in the control group on the 4th and 6th days after onset (P <0.01, P <0.05) Day 6 and gradually picked up. Serum NO levels in mild and severe patients were not significantly reduced (P> 0.05). Conclusion: Acanthopanax senticosus may have protective effect on secondary brain injury after SAH