环糊精是将淀粉用土壤中分离的嗜碱性芽孢杆菌,经培养得到的碱性淀粉酶水解环合而成。常见有α、β、γ三种环糊精,其中以包合力最强的(β-cyclcdextrin)最为常用。它能使药物呈分子状分布,分散效果好,易于吸收,且因其剂型类似微型胶囊,而使药物释放缓慢副反应降低。 Cyclodextrins are Bacillus alkalophilic bacteria isolated from the soil and cyclized by alkaline amylase hydrolyzed by culture. There are three types of cyclodextrins, α, β, and γ. Among them, β-cyclcdextrin is the most commonly used. It can make the drug distribution in the form of molecules, good dispersion effect, easy to absorb, and because its dosage form is similar to microcapsules, it slows down the side reactions of slow drug release.