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自从1880年Stumpell首先报告了遗传性痉挛性截瘫一个家族之后,至1963年Roe统计见于世界文献已有215个家系患者。1980年前国内有三篇[2.3.4]文献。报告了三个家族25例患者。现将我们调查的一个家族三代9例患者的临床观察报告如下:
Since Stumpell first reported a family of hereditary spastic paraplegia in 1880, Roe’s statistics in 1963 were found in the world literature of 215 pedigree patients. By 1980 there were three domestic [2.3.4] documents. Twenty-five patients were reported in three families. Now we investigate a family of three generations of 9 patients clinical observation report as follows: