高致病性禽流感是由高致病性禽流感病毒所引起的禽类烈性传染病。近年来,世界各国都在积极研制人用禽流感疫苗,但与之相关的疫苗安全性评价的报道却较少。因此,我们对家蚕生物反应器生产的新型人用禽流感疫苗进行了猴一般毒性实验,为其临床上的应用提供科学依据。1材料与方法1 HPAI is a poultry infectious disease caused by the highly pathogenic avian influenza virus. In recent years, all countries in the world are actively developing human bird flu vaccines, but there are few reports on vaccine safety evaluation. Therefore, we conducted a general toxicity test on the new type of human bird flu vaccine produced by silkworm bioreactor to provide a scientific basis for its clinical application. 1 Materials and methods 1