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A new chalcone glucoside, androechin, and a known flavone glucoside, echioidinin 5-O-gluco side, were isolated from the whole plant of Andrographis echioides. Androechin was character ized as 2,2’,6’-trihydroxy-4’-methoxychalcone 2’-O-,β-D-glucopyranoside by spectral and chemical studies.