毛间质细胞瘤也称Malherbe钙化上皮瘤,是一种来源于毛细胞的良性肿瘤。临床少见但不十分少见。常被误诊为囊肿、钙化淋巴结、血肿或血管瘤钙化及腮腺肿瘤,此种肿瘤50％以上发生于头颈部。40％发生于10岁以下之小儿。但耳鼻喉科和儿科文献很少叙述。 1980年Malherbe等首先描述此病。1933年Chin通过文献复习,推测该肿瘤来源于皮肤或皮肤属器。1961年Forbis和Helwig肯定了来源于毛间质细胞假说,并命名为毛间质细胞瘤。以后为电子显微镜与组织化学 The stromal cell tumor, also known as Malherbe calcified epithelioma, is a benign tumor derived from hair cells. Clinical rare but not very rare. It is often misdiagnosed as cysts, calcified lymph nodes, hematoma, calcification of hemangiomas, and salivary gland tumors. More than 50% of these tumors occur in the head and neck. 40% occur in children under 10 years of age. However, ENT literature is rarely described. In 1980, Malherbe et al. first described the disease. In 1933, Chin reviewed the literature and speculated that the tumor originated from the skin or skin genitalia. In 1961, Forbis and Helwig affirmed the hypothesis that it was derived from the interstitial cells and named it stromal cell tumor. After the electron microscope and histochemistry