论文部分内容阅读
目的探讨三维适形放疗治疗外耳道中耳癌的临床疗效。方法应用三维适形放疗:采用CT扫描,层厚、层距均为3～5mm,CT扫描资料经光缆传送至三维适形治疗计划系统,勾画靶区,范围为CT上可见病变外放1～1.5cm,总量达65～70Gy。结果 12例患者放疗后随访,最长随访3年,2例死于肿瘤复发,1例死于肿瘤脑转移,1例死于肿瘤肺转移,总的3年生存率为66.7%。肿瘤部位在外耳道和外耳道及中耳均有肿瘤的3年生存率分别为71.4%和50.0%。结论外耳道中耳癌采用三维适形放疗3年生存率较文献报道相似,且没有手术及普通放疗的副作用,其治疗副作用能为大多患者所耐受,是一种较为理想的治疗方法.
Objective To investigate the clinical effect of three-dimensional conformal radiotherapy on middle ear cancers of external auditory canal. Methods Three-dimensional conformal radiotherapy was applied. CT scanning, layer thickness and layer spacing were all 3 ~ 5mm. The CT scan data were transmitted to the three-dimensional conformal treatment planning system via optical fiber cable. The target area was delineated in the range of 1 ~ 1.5cm, the total amount of 65 ~ 70Gy. Results 12 patients were followed up after radiotherapy for up to 3 years, 2 died of tumor recurrence, 1 died of tumor brain metastasis and 1 died of tumor lung metastasis. The overall 3-year survival rate was 66.7%. The 3-year survival rates of tumor at the external auditory canal, external auditory canal and middle ear were 71.4% and 50.0% respectively. Conclusions The 3-year survival rate of 3-D conformal radiotherapy for middle ear canal of external auditory canal is similar to that reported in the literature, and there is no side effect of surgery and general radiotherapy. Its side effects can be tolerated in most patients, which is an ideal treatment.